Cancer is a very rare disease in children. There have been impressive gains in survival in recent years, and these have been achieved through the use of chemotherapy and national and international clinical trials. The diagnosis of cancer in a child imposes considerable stress on the whole family. In the immediate time after diagnosis, parents must learn about the disease and its treatment, explain what is happening to the child, and make arrangements for the care of other children in the family. For the child, treatment is associated with many side effects depending on the specific drugs used. In addition, the child is prone to infection and therefore is likely to miss a lot of school and other activities. For all these reasons, doctors and families have become aware that cancer has huge implications for the quality of the child's life. different stages of the disease process. Comprehensive reviews are provided about the impact on the child's physical activity, social life, and school and educational achievements. Special consideration is given to children with leukaemia (one of the more common cancers) and brain tumours.