Bioinformatics: A Modern Approach (Paperback)


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Bioinformatics: A Modern Approach Book Description

About the Book :

Being an interdisciplinary subject, Bioinformatics is today covering a range of interest both among the students and teaching communities. Taking this increasing interest into account, this book gives a comprehensive introduction to the subject. The text not only deals with the basic concepts but it also emphasizes the technical and practical aspects of the subject. The book covers the computational tools in bioinformatics, algorithmic aspects as well as technological aspects. Besides it gives a clear exposition of Viterbi algorithm, Hidden Markov models, UPGMA, FM algorithm, heuristic, developing and using substitution matrices, HMMs and derivation of a number of standard formulae in information theory and statistics. Finally the text focusses on the technological aspects of bioinformatics such as sequencing through shot gun methods, microarrays, with a variety of unsupervised methods in data analysis with examples, as well as interdisciplinary research in systems biology. The book is primarily intended as a text for the students of Computer Science, Information Technology, undergraduate students of Bioinformatics, PGDCA and biological sciences and biotechnology. The book should also be of considerable interest for research scientist in Chemistry and Pharmacy.

About the Author :

VITTAL R. SRINIVAS (M.S., M.Engg., Rensselaer Polytechnic Institute, New York, USA), was a Project Officer in the Department of Biotechnology, Indian Institute of Technology Madras. He completed dual masters level education from Rensselaer Polytechnic Institute, New York, USA and has done training in biological applications on problems related to medicine mainly using computational approaches. Currently he is pursuing research towards his doctoral degree at Rice University, Houston, Texas. An interdisciplinary scientist, with varied background that range, from engineering to cell biology and bioinformatics. Mr. Vittal Srinivas prefers to be called an engineer-biologist. He is interested in solving problems that impinges on molecular medicine and etiology of diseases using a multidisciplinary approach.

Features :

  • Provides an algorithmic approach to bioinformatics coupled with latest technologies.
  • Many complex ideas have been simplified.
  • Includes topics in sequence searching, sequence comparison and tree construction.
  • Contains ample model questions and sample projects at the end of the book.


Contents :


List of Figures.

List of Tables.

Preface.

Acknowledgements.

Prologue.

Introduction.

Part I: Introduction to Bioinformatics-

1. Getting Started with Linux.

Part II: Programming, Database Management and Information Theory-

2. World Wide Web.
3. Perl and Java.
4. Information Theory.

Part III: Sequence Databases and Sequence Analysis-

5. National Center for Biotechnology Information (NCBI).
6. Blast and Fasta: A Search for Similarity.

Part IV: Multiple Sequence Alignment, Phylogenetic Analysis and Gene Prediction-

7. Pairwise Sequence Alignment and Dynamic Programming.
8. Phylogeny.
9. Gene Prediction.

Part V: Protein Databases, Protein Domain Searching, and Structure Prediction-

10. Protein Data Bank (PDB).
11. Domain Assignment and Searching.
12. Native Structure Prediction and Protein Folding Prediction.

Part VI: Sequencing & Genome Mapping-

13. Genome Sequencing.
14. Maps.

Part VII: Microarrays & Systems Biology-

15. Why the Buzz About Microarrays?
16. Microarray Design, Data Acquisition and Analysis.
17. Proteomics.
18. Systems Biology-The Holy Grail of Integration.
19. Public Domain Databases and Analysis Tools: A Compendium.

Model Questions.

Appendix: Fundamentals of Probability.

Epilogue.

Bibliography

Index.

Book Details


Title: Bioinformatics: A Modern Approach
Publisher: PHI
Edition: Paperback
ISBN:

8120328582

EAN:

9788120328587

No. of Pages: 280
Deliverable Countries: This product ships to India, Sri Lanka.

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The book Bioinformatics: A Modern Approach by (author) is published or distributed by PHI [8120328582, 9788120328587]. This particular edition was published on or around 2005-1-1 date. Bioinformatics: A Modern Approach has Paperback binding and this format has 280 number of pages of content for use.
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