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Intrinsic Factor

Intrinsic Factor (Paperback)

By Editor : Lambert M Surhone , Mariam T Tennoe , Susan F Henssonow 
R 2,825 ($ 48.03) (£ 26.25)
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Intrinsic Factor Description

High Quality Content by WIKIPEDIA articles! Intrinsic factor (if) also known as gastric intrinsic factor (GIF) is a glycoprotein produced by the parietal cells of the stomach. It is necessary for the absorption of vitamin B12 later on in the terminal ileum. In humans, the gastric intrinsic factor protein is encoded by the GIF gene. Upon entry into the stomach, vitamin B12 becomes bound to haptocorrin (R factor), a glycoprotein. The resulting complex enters the duodenum, where pancreatic enzymes digest haptocorrin. In the less acidic environment of the small intestine, B12 can then bind to intrinsic factor. This new complex travels to the ileum, where special epithelial cells endocytose them. Inside the cell, B12 dissociates once again and binds to another protein, transcobalamin II. The new complex can exit the epithelial cells to enter the liver.

Book Details


Title: Intrinsic Factor
Publisher: VDM Verlag Dr. Mueller AG & Co. Kg
Editor: Lambert M Surhone , Mariam T Tennoe , Susan F Henssonow
Edition: Paperback
Language: English
ISBN: 6133080299
EAN: 9786133080294
No. of Units: 1
No. of Pages: 76
Publish Date: 2010-9-21
Binding: Paperback
Deliverable Countries: This product ships to Restricted International (Books).

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Biology - General  >  Life Sciences  >  Science

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