Alice fights alongside a resistance movement in the continuing battle against the Umbrella Corporation and the undead.
The story then switches to a suburban housewife who appears to be Alice living with her husband Todd (Oded Fehr) and deaf daughter Becky (Aryana Engineer). However, this idyllic life is disrupted when zombies attack and kill Todd. Alice and Becky escape to the streets and are rescued by Rain Ocampo (Michelle Rodriguez), who lets them ride in her car. As the three escape, they are hit by a truck, knocking Rain unconscious while Alice and Becky escape. Alice runs and is attacked by a zombified Todd.