Myriad infections and immunologic diseases threaten hundreds of millions of people worldwide. A complex mix of ecology, evolution and culture produces the conditions in which disease-causing microbes can thrive and infectious diseases can emerge suddenly spread rapidly and are often difficult to control The Year in Infection 2003 is an important addition to the series, dedicated to the rapid publication of the most up to date information in this field. It contains a wide range of articles and topical reviews dealing with both clinical and experimental aspects of Infection. Part One provides an overview of mycology examining the latest advances in antifungal therapies, issues in haematology and nosocomial concerns. The second section tackles the current issues in the management of HIV and includes discussion of the rising risk of HIV for women and the effect of the disease on children. Section three reviews the emerging problems with Gram positive bacteria including reports on pneumococcal disease and MRSA Infections. The final section focuses on the continued need to prevent, and control, re-emerging and new infections. The Year in Infection is a highly informative serial that draws on the expertise of a leading team and will prove an invaluable ongoing resource for Physicians in their daily practice.