Drug Stereochemistry: Analytical Methods and Pharmacology

Drug Stereochemistry: Analytical Methods and Pharmacology (Hardcover)

By Irving W Wainer , W J Lough , Krzysztof Jozwiak 
Publisher: Informa Healthcare
Edition: Hardcover
Edition Number: 3
Language: English
ISBN: 1420092383
EAN: 9781420092387
No. of Units: 1
No. of Pages: 332
Publish Date: 2012-4-17
Binding: Hardcover
Ships to India.


Updated to reflect modern advances in the techniques and methodology of drug stereochemistry, the Third Edition comprehensively presents all aspects of chiral drugs from scientific, academic, governmental, industrial, and clinical points of view. This stand-alone text covers the lifespan of stereochemistry, from its early history, including an overview of terms and concepts, to the current drug development process, legal and regulatory issues, and the new stereoisomeric drugs.
New topics in the Third Edition include:
The use of enzymes in the synthesis and resolution of enantiometrically pure compounds in drug discovery
How stereochemistry impacts decisions made in the Absorption, Distribution, Metabolism, Excretion, and Toxicity (ADMET) stages of drug discovery
A chapter on pharmacokinetics and pharmacodynamics that discusses the issues faced during the final stages of the drug development process
The impact of International Conference on Harmonisation on the use of single isomer drugs
Racemic switches
The concept of molecular chiral recognition and how it affects the separation and behavior of stereochemically pure drugs
A chapter on the legal perspectives of patent issues surrounding racemic switches and the marketing of single enantiomer switches
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Title: Drug Stereochemistry: Analytical Methods and Pharmacology
Publisher: Informa Healthcare
Author: Irving W Wainer , W J Lough , Krzysztof Jozwiak
Edition: Hardcover
Edition Number: 3
Language: English
ISBN: 1420092383
EAN: 9781420092387
No. of Units: 1
No. of Pages: 332
Publish Date: 2012-4-17
Binding: Hardcover


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