Protease Inhibitors in AIDS Therapy

Protease Inhibitors in AIDS Therapy (Hardcover)

By Richard C Ogden , Charles W Flexner , Ogden C Ogden 
Publisher: CRC Press
Edition: Hardcover
Language: English
ISBN: 0824704614
EAN: 9780824704612
No. of Units: 1
No. of Pages: 310
Publish Date: 2001-01-31
Binding: Hardcover
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Description

Details the evolution of HIV protease inhibitors from molecular development through medical applications! Considering the latest class of revolutionary drugs fighting against HIV infection and AIDS, this comprehensive reference thoroughly examines the development and properties of HIV protease inhibitors from clinical and scientific perspectives, discussing how protease inhibitors changed the FDA approval process-enhancing the collaboration between regulatory authorities and drug developers. Spotlights protease inhibitors as the cornerstone drugs of the first HAART regimens-key components of long-term viral suppression and immune restoration, and in secondary and tertiary regimens! Evaluating protease inhibitors as therapeutic options and research tools, Protease Inhibitors in AIDS Therapy -reviews the impact of advances in recombinant DNA technology for understanding and treating HIV and AIDS -highlights a variety of strategies and techniques for drug discovery and development illustrated by success stories of pharmaceutical companies and biotechnology start-up firms -summarizes the pharmacokinetics, metabolism, and drug interactions of protease inhibitors -details preliminary clinical studies on oral bioavailability, pharmacokinetic profiling, efficacy, resistance, and tolerability -describes available efficacy data for marketed inhibitors and those in clinical development -reports on efforts to manage antiviral resistance in the clinic and improve patient adherence to complex drug therapy -and more! Containing more than 600 helpful literature references, drawings, photographs, and tables, Protease Inhibitors in AIDS Therapy serves for an essential reference for infectious diseasespecialists, epidemiologists, virologists, immunologists, pharmacologists, medicinal chemists and biochemists, microbiologists, hematologists, hepatologists, and medical students in these disciplines.
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Specification

Title: Protease Inhibitors in AIDS Therapy
Publisher: CRC Press
Author: Richard C Ogden , Charles W Flexner , Ogden C Ogden
Edition: Hardcover
Language: English
ISBN: 0824704614
EAN: 9780824704612
No. of Units: 1
No. of Pages: 310
Publish Date: 2001-01-31
Binding: Hardcover

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